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Topiramate is a white crystalline powder with a bitter taste. Topiramate is most soluble in alkaline solutions containing sodium hydroxide or sodium phosphate and having a pH of 9 to 10. It is freely soluble in acetone, chloroform, dimethylsulfoxide, and ethanol.

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Bipolar disorder is commonly treated with Topamax, although it is generally paired with other medications such as SSRIís. While it is often used to treat bipolar, studies have not proven that it is particularly useful in doing so, though many patients and doctors report being successful in treating the condition with the medication. Doctors will often try Topamax when other treatment options have failed.

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